The Celltechgen™In Situ Cell Death Detection Kit, FITC


Cleavage of genomic DNA during apoptosis will produce double-stranded, DNA fragments (mono- and oligonucleosomes) as well as single strand breaks (“nicks”) in various molecular weight DNA. Those DNA strand breaks can be identified by labeling free 3’-OH termini by Terminal deoxynucleotidyl transferase (TdT) with Fluorescein-conjugated nucleotides in a template-independent manner (TUNEL-reaction), the incorporated Fluorescein can be detected by Fluorescein fluorescence and can be analyzed under microscope.

SKU: CTG-AK0001 Category: