CD43 (leukosialin, sialophorin, or leukocyte sialoglycoprotein) is a cell surface glycoprotein that is expressed on all thymocytes, T-cells, and cells of myeloid lineage. CD43 antibody can be useful in the diagnosis of T-cell lymphoma and a subset of B-cell lymphoma. CD43 expression in lymphomas is highly correlated with CD5; thus, most T-cell malignancies and a group of small lymphocyte B-cell malignancies (CLL/SLL, mantle cell lymphoma, and prolymphocytic leukemia (PLL)) are often positive, whereas follicular lymphoma is rarely positive. CD43 is also positive in about 50% of cases of Burkitt lymphoma.
KIT COMPONENTS (100 reactions)
- 50x DAB Chromogen 1 x 0.5ml
- Biotinylated goat anti-rabbit IgG(H+L) 1 x 15ml
- DAB substrate 1 x 15ml
- Hydrogen Peroxide Block 1 x 15ml
- Protein block 1 x 15ml
- Streptavidin Peroxidase 1 x 15ml
- Rabbit anti-human CD43
Store at +4°C. Please refer to protocols.
The products is “”FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES”””
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