DESCRIPTION
Blasticidin S Hydrochloride belongs to a group of cytosine amino nucleoside antibiotics.The compound Blasticidin S has a wide spectrum of antimicrobial activity and acts on prokaryotic and eukaryotic organisms by inhibiting protein
| Synonyms: | Bla-S,Blasticidin S, monohydrochloride (8CI) |
| IUPAC Name: | (2S,3S, 6R)-3-[[(3R)-3-amino-5-[carbamimidoyl(methyl)amino]pentanoyl]amino]-6-(4-amino-2-oxopyrimidin-1-yl)-3,6-dihydro-2H-pyran-2-carboxylicacid; hydrochloride |
| Molecular Formula: | C17H26N8O5 (HCl) |
| Molecular weight: | 458.90 |
| Source: | Streptomyces griseochromogenes |
| Appearance: | Off-white |
| Brand/grade: | For research |
| Purity by HPLC: | ≥98% |
| Crystallinity: | Amorphous |
| Purity By TLC: | Single spot on TLC plates, by multiple methods |
| Melting point: | Gradual decomposition with charring between 210°C to 250°C |
| Solubility test: | Clear colorless solution at 10 mg/ml Acetic acid or Water. |
| Solubility ( literature ): | Soluble in water, Acetic acid. Slightly soluble in acidified methanol. |
| Compound Classification: | Cytosine amino nucleoside type antibiotic |
Applications:
Blasticidin-S is a commonly used tool in genetic engineering. Blasticidin-S inhibits protein synthesis in both prokaryotic and eukaryotic cells. It is common method to include a gene for Blasticidin S resistance into the plasmid being inserted into the target cells, and then to apply Blasticidin S to the culture to select these cells that have acquired that immunity. The Blasticidin S gene resistance gene (BSR), found in Bacillus cereus K55-S1, has been used in multiple studies for its use as a selective compound. Another antibiotic that belongs to the family of nucleosides is Puromycin.
SIZE
10mL ; 20mL
STORAGE
Refrigerate upon arrival, at +2°C to +8°C
USAGE
Celltechgen provides high-quality reagents and materials for research use only. For proper handling of potentially hazardous chemicals, please request the Safety Data Sheet (SDS) provided for the product.
Celltechgen provides high-quality reagents and materials for research use only. For proper handling of potentially hazardous chemicals, please request the Safety Data Sheet (SDS) provided for the product.
| Applications | Deplete |
|---|---|
| Categories | |
| Research area | |
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