Simian Virus 40 (SV40) is a polyomavirus that is found in both monkeys and humans. Like other polyomaviruses, SV40 is a DNA virus that has the potential to cause tumors. SV40 is believed to suppress the tumor-suppressing p53 in humans. A mutated p53 gene may contribute to uncontrolled cellular proliferation, leading to a tumor. The hypothesis that SV40 might cause cancer in humans has been a particularly controversial area of research. Some research has suggested that SV40 is associated with brain tumors, bone cancers, non-Hodgkin lymphoma and malignant mesothelioma. This antibody shows cross-reactivity to BK and JC virus, and some use it a surrogate to detect these viruses.
KIT COMPONENTS (100 reactions)
- 50x DAB Chromogen 1 x 0.5ml
- Biotinylated goat anti-rabbit IgG(H+L) 1 x 15ml
- DAB substrate 1 x 15ml
- Hydrogen Peroxide Block 1 x 15ml
- Protein block 1 x 15ml
- Streptavidin Peroxidase 1 x 15ml
- Rabbit anti-human Simian Virus 40 (SV40)
Store at +4°C. Please refer to protocols.
The products is “”FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES”””