Napsin A has a specific function in normal alveolar epithelium and is proposed to play a role in the proteolytic processing of surfactant precursors. Napsin A is reported to be predominantly expressed in lamellar bodies of type II pneumocytes, secondary lysosomes of alveolar macrophages, respiratory epithelium of terminal and respiratory bronchioles, plasma cells, and within a subset of lymphocytes in normal lung as well as in epithelial cells of renal tubules in normal kidney. It is weakly expressed in normal spleen. Past studies have also reported that Napsin A is expressed in most primary lung adenocarcinomas. Napsin A expression may also be seen in renal carcinoma.
KIT COMPONENTS (100 reactions)
- 50x DAB Chromogen 1 x 0.5ml
- Biotinylated goat anti-rabbit IgG(H+L) 1 x 15ml
- DAB substrate 1 x 15ml
- Hydrogen Peroxide Block 1 x 15ml
- Protein block 1 x 15ml
- Streptavidin Peroxidase 1 x 15ml
- Rabbit anti-human Napsin A
Store at +4°C. Please refer to protocols.
The products is “”FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES”””