Glutathione S Transferase Pi (GSTpi) is a cytosolic enzyme that catalyzes the conjugation of toxic compounds to glutathione for transport out of the cell. Increased expression of GSTp has been demonstrated to show increased resistance to alkylating agents, such as cyclophosphamide, ifosphamide, and melphalan. GSTp is widely distributed throughout the body and has been identified in epithelial elements of thyroid, urinary, digestive track, and hepatic bile ducts. Adenocarcinomas of the stomach, kidney, uterus and ovary, as well as squamous cell tumors of the head and neck, melanomas, and carcinoid tumors of the lung all demonstrate reactivity with this antibody.
KIT COMPONENTS (100 reactions)
- 50x DAB Chromogen 1 x 0.5ml
- Biotinylated goat anti-rabbit IgG(H+L) 1 x 15ml
- DAB substrate 1 x 15ml
- Hydrogen Peroxide Block 1 x 15ml
- Protein block 1 x 15ml
- Streptavidin Peroxidase 1 x 15ml
- Rabbit anti-human GST Pi
Store at +4°C. Please refer to protocols.
The products is “”FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC PROCEDURES”””
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